产品编号：I666655

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	I666655
名称:	Intedanib N-β-D-Glucuronide
别名:	(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester N-β-D-Glucuronide; BIBF 1120 N-β-D-Glucuronide; Ofev N-β-D-Glucuronide; Vargatef N-β-D-Glucuronide; Nintedanib N-β-D-Glucuronide
分子式:	C₃₆H₃₉N₅O₁₀
分子量:	701.72
种类:	Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
应用:	Intedanib N-β-D-Glucuronide is a possible metabolite of Intedanib (I666650), an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.
参考文献	Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)