产品编号：I125385

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	I125385
名称:	Imidazolidine-2,4-dione Ketoconazole
别名:	HLI 151; 1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-[(2,5-dioxo-1-imidazolidinyl)methyl]-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; 3-(((2R,4S)-4-((4-(4-Acetylpiperazin-1-yl)phenoxy)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl)methyl)imidazolidine-2,4-dione
CAS号:	96734-91-7
分子式:	C₂₆H₂₈Cl₂N₄O₆
分子量:	563.43
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Imidazolidine-2,4-dione Ketoconazole is a metabolite of Ketoconazole (K186000). Ketoconazole is an orally active 5-lipoxygenase and thromboxane synthase inhibitor. Also an Inhibitor of exosome secretion.
参考文献	Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986); Scientific Reports 8: 8161 (2018)