产品编号：H998025
产品规格：10mg
产品价格：面议
| 标准品编号: | H998025 |
| 名称: | Hymenialdisine Analogue #1 |
| 别名: | 5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidene)-3,4,5,10-tetrahydro-2H-azepino[3,4-b]indol-1-one |
| CAS号: | 693222-51-4 |
| 分子式: | C₁₅H₁₃N₅O₂ |
| 外观: | Light Yellow to Yellow Solid |
| 分子量: | 295.3 |
| 储存: | -20˚C Freezer |
| 溶解度: | DMSO (Slightly) |
| 种类: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | The indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. This compound exhibits very potent inhibition of Chk2 activity in the low nanomolar range (IC50=8nM). Exhibits an increased selectivity for the checkpoint kinases over natural Hymenialdisine. |
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