产品编号：H943202

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	H943202
名称:	Hydroxy Ibuprofen-d3
别名:	4-(3-Hydroxy-2-methylpropyl)-α-methyl-benzeneacetic-d3 Acid; 2,4'-(2-Hydroxymethylpropyl)phenylpropionic-d3 Acid;
参考CAS号:	Unlabelled: 53949-54-5
分子式:	C₁₃H₁₅D₃O₃
分子量:	225.3
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled Hydroxy Ibuprofen is a metabolite of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
参考文献	Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); Neunzig, I. et al.: J. Biotechnol., 157, 417 (2012);