产品编号：H942103

产品规格：2.5mg

产品价格：面议

---

产品详情

标准品编号:	H942103
名称:	2-Hydroxy Estradiol 1-N3-Adenine
别名:	(8R,9S,13S,14S,17S)-1-(6-Amino-3H-purin-3-yl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-2,3,17-triol
CAS号:	914934-02-4
分子式:	C₂₃H₂₇N₅O₃
分子量:	421.49
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.
参考文献	Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002), Paula, M. et al.: J Steroid Biochem. Mol. Biol., 101, 204 (2006);