产品编号：H804585

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	H804585
名称:	(R)-2-(2-((hydroxymethyl)amino)-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)-N-methylacetamide
分子式:	C₁₁H₁₇N₃O₂S
分子量:	255.34
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(R)-2-(2-((hydroxymethyl)amino)-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)-N-methylacetamide is an adduct impurity of Pramipexole (P700750) formaldehyde. Pramipexole (P700750) is a dopamine-D2-receptor agonist. Antiparkinsonian. Pramipexole (Mirapex, Mirapexin, Sifrol) is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).[1] It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.
参考文献	Mierau, J., et al.: J. Med. Chem., 30, 494 (1987), Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)