产品编号：G929500

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	G929500
名称:	GW 610
别名:	2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole;
CAS号:	872726-44-8
分子式:	C₁₅H₁₂FNO₂S
分子量:	289.32
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	GW 610 is a fluorinated 2-arylbenzothiazole and potential antitumor drug, which shows potent and selective inhibitory activity against breast, lung, and colon cancer cell lines. Studies suggest that the species-specific partial agonism of the aryl hydrocarbon receptor shown by GW 610 plays an important role in its anti-proliferative activity.
参考文献	Wang, M. et al.: Bioorg. Med. Chem., 14, 8599 (2006); Bazzi, R. et al.: Toxicol. Appl. Pharmacol., 237, 102 (2009); Wang, K. et al.: Chem. Res. Toxicol., 25, 1740 (2012);