产品编号:E957300
产品规格:5mg
产品价格:面议
| 标准品编号: | E957300 |
| 名称: | Exenatide Acetate |
| 别名: | Exendin-4; |
| CAS号: | 141732-76-5 |
| 参考CAS: | freebase: 141758-74-9 |
| 分子式: | 3 |
| 外观: | 白色至白色固体 |
| 熔点: | >209°C (dec.) |
| 分子量: | 4246.62 |
| 储存: | 冰箱保存 |
| 溶解度: | Acetonitrile (Slightly), Water (Slightly) |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II. |
| 参考文献 | |