产品编号：E678310

产品规格：1g

产品价格：面议

---

产品详情

标准品编号:	E678310
名称:	(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic Acid 1,1-Dimethylethyl Ester
别名:	[3R-(3α,4α)]-[partial]-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS号:	201856-57-7
分子式:	C₁₈H₂₅NO₅
分子量:	335.39
种类:	Building Blocks;
应用:	(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is used as a reagent in the synthesis of abeo-taxane derivatives that possess broad inhibitory effects against proliferation of colon cancer, melanoma, and renal cancer cell lines. (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is also used as a reagent in the synthesis of a novel D-ring modified Docetaxel (D494420) analogue which has proven to have equipotent cytotoxicity in relation to Paclitaxel (P132500) towards cancer cell lines.
参考文献	Zhao, Y., et al.: J. Med. Chem., 56, 4749 (2013); Gao, F., et al.: Org. Biomol. Chem., 10, 361 (2012)