产品编号：E615200

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	E615200
名称:	Erismodegib
别名:	rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-1,1'-biphenyl]-3-carboxamide; LDE 225; NVP-LDE 225; Odomzo; Sonidegib;
CAS号:	956697-53-3
分子式:	C₂₆H₂₆F₃N₃O₃
外观:	Light Purple Solid
熔点:	154-157°C
分子量:	485.5
储存:	冰箱保存
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Research Tools; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A potent, selective and orally bioavailable Smoothened (SMO) antagonist; it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO). Antineoplastic. Potent Hedgehog inhibitor.
参考文献	Berman, D., et al.: Science, 297, 1559 (2002), Varjosalo, M., et al.: Cell, 133, 537 (2008), Theunissen, J., et al.: Cancer Res., 69, 6007 (2009),

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