产品编号：E588995

产品规格：

产品价格：面议

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产品详情

标准品编号:	E588995
名称:	Epothilone C
别名:	[4S-[4R*,7S*,8R*,9R*,13Z,16R*(E)]]-4,8-Dihydroxy-5,5,7,9-tetramethyl-16-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-oxacyclohexadec-13-ene-2,6-dione; (4S,7R,8S,9S,13Z,16S)-4,8-Dihydroxy-5,5,7,9-tetramethyl-16-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]oxacyclohexadec-13-ene-2,6-dione; (-)-Deoxyepothilone A; (-)-Desoxyepothilone A; Desoxyepothilone A; Epo C
CAS号:	186692-73-9
分子式:	C₂₆H₃₉NO₅S
分子量:	477.66
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Epothilone C is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.
参考文献	Canta, A., et al.:Curr. Med. Chem 16, 1315 (2009);Bollag, D.M., et al.: Cancer. Res., 55, 2325 (1995), Hardt, I.H., et al.: J. Nat. Prod., 64, 847 (2001), Gerth, K., et al.: J. Antibiot., 55, 41, 45 (2002)