产品编号：E588055

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	E588055
名称:	4,5α-Epoxy Eplerenone
别名:	(4α,5α,7α,11α,17α)-4,5:9,11-Diepoxy-17-hydroxy-3-oxo-γ-lactone-methylester-pregnane-7,21-dicarboxylic Acid
CAS号:	209253-73-6
分子式:	C₂₄H₃₀O₇
分子量:	430.49
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
应用:	4,5α-Epoxy Eplerenone is an impurity of Eplerenone (E588775), a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
参考文献	de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),