产品编号：E525980

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	E525980
名称:	Emtricitabine O-p-​Toluenesulfonate
别名:	((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl 4-methylbenzenesulfonate
分子式:	C₁₅H₁₆FN₃O₅S₂
外观:	Light Brown Solid
分子量:	401.43
储存:	-20°C Freezer
溶解度:	Dichloromethane; Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
应用:	Emtricitabine O-p-​Toluenesulfonate is an intermediate in the synthesis of Emtricitabine Diphosphate Triethylammonium Salt (E524978), a metabolite of Emtricitabine (E525000), which is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
参考文献	FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)