产品编号：D528805
产品规格：2.5mg
产品价格：面议
| 标准品编号: | D528805 |
| 名称: | Dolutegravir Sodium Salt |
| 别名: | Dolutegravir sodium; GSK 1349572A; N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Sodium Salt |
| CAS号: | 1051375-19-9 |
| 参考CAS: | 1051375-16-6 free amine |
| 分子式: | C₂₀H₁₈F₂N₃NaO₅ |
| 外观: | 白色至Green Solid |
| 熔点: | >300ºC |
| 分子量: | 441.36 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. |
| 参考文献 | |
