产品编号：D486998

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	D486998
名称:	2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione
别名:	2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione
CAS号:	835616-60-9
分子式:	C₁₃H₉FN₂O₄
外观:	白色至白色固体
熔点:	254-256°C
分子量:	276.22
储存:	-20°C Freezer
溶解性:	Dichloromethane (Slightly, Heated), DMSO (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of N-[2-Aminoethyl] Pomalidomide TFA Salt (A6095150. N-[2-Aminoethyl] Pomalidomide TFA is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an anti-inflammatory and anti-tumor agent used in the treatment of multiple myeloma.
参考文献	Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)