产品编号：D474092

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D474092
名称:	(3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-cholest-5-en-24-one-d3
分子式:	C₃₃H₅₅D₃O₂Si
外观:	白色固体
分子量:	517.92
溶解性:	Chloroform, Dichloromethane, Ethyl Acetate
种类:	Standards; Steroids; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-cholest-5-en-24-one-d3 is the isotope labelled analog of (3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-cholest-5-en-24-one. (3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-cholest-5-en-24-one is an intermediate in the synthesis of 24-Hydroxycholesterol (H918040), which is the main cholesterol elimination product of the brain and was found to be increased in serum of Alzheimer patients.
参考文献	Kolsch, H., et al.: J. Neural. Transm., 108, 475 (2001); Gamba, P., et al.: Aging. Cell., 10, 403 (2011); Seet, R.C.S., et al.: Free. Rad. Biol. Med., 48, 560 (2010);