产品编号：D473365

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	D473365
名称:	(αR,δS,γR)-δ-[[(1,1-Dimethylethoxy)carbonyl]amino]-γ-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-α-(phenylmethyl)benzenehexanoic Acid
别名:	(αR,γR,δS)-δ-[[(1,1-Dimethylethoxy)carbonyl]amino]-γ-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-α-(phenylmethyl)benzenehexanoic Acid; [αR-(αR*,γR*,δS*)]-δ-[[(1,1-Dimethylethoxy)carbonyl]amino]-γ-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-α-(phenylmethyl)benzenehexanoic Acid
CAS号:	98818-49-6
分子式:	C₃₀H₄₅NO₅Si
外观:	White Foam
分子量:	527.77
溶解性:	Ethyl Acetate
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(αR,δS,γR)-δ-[[(1,1-Dimethylethoxy)carbonyl]amino]-γ-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-α-(phenylmethyl)benzenehexanoic Acid is an intermediate in the synthesis of γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (Aβ), the major causative agent in Alzheimer disease (AD).
参考文献	Crump, C.J., et al.: Biorg. Med. Chem. Lett., 22, 2997 (2012);