产品编号：D470930

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D470930
名称:	17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride
别名:	17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin Hydrochloride; 17-N-(2-Dimethylaminoethylamino)-17-demethoxygeldanamycin Hydrochloride; 17-[2-(Dimethylamino)ethylamino]-17-desmethylgeldanamycin Hydrochloride; Alvespimycin Hydrochloride; DMAG Hydrochloride; NSC 707545 Hydrochloride; 17-DMAG Hydrochloride;
CAS号:	467214-21-7
参考CAS号:	467214-20-6-free base
分子式:	C₃₂H₄₉ClN₄O₈
外观:	Very Dark Purple Solid
熔点:	>270°C (dec.)
分子量:	653.21
储存:	-20˚C Freezer
溶解性:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	17-DMAG is an analogue of Gelamycin (G304500) and 17-(Allylamino)geldanamycin (A549650). 17-DMAG acts as a Hsp90 inhibitor and displays more potent antitumor activity than 17-AAG.
参考文献	Dote, H. et al.: Cancer Res., 66, 9211 (2006); Smith, V. et al.: Cancer Chemother. Pharmacol., 56, 126 (2005); Egorin, M.J. et al.: Cancer Chemother. Pharmacol., 49, 7 (2002);