产品编号：D460420

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	D460420
名称:	(S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylacetamide
参考CAS号:	Free base: 866783-12-2
分子式:	C₁₄H₁₉NO₃
外观:	Clear Colourless to Pale Yellow Thick Oil
分子量:	249.31
储存:	Amber Vial, -20°C Freezer
溶解性:	Chloroform (Slightly), Methanol (Slightly)
稳定性:	Light Sensitive
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylacetamide is a derivative of (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane (D461760, HCl); an intermediate in the synthesis of Ivabradine (I940500, HCl) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also an antianginal.
参考文献	Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994); Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998); Borer, J.S., et al.: Circulation, 107, 817 (2003); DiFrancesco, D., et al.: Drugs, 64, 1757 (2004)