产品编号：D454135

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	D454135
名称:	(αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile
别名:	Entacapone EP Impurity H
CAS号:	1150310-15-8
分子式:	C₁₅H₁₅N₃O₅
分子量:	317.3
种类:	Building Blocks;
应用:	(αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
参考文献	Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),