产品编号：D448593

产品规格：1000mg

产品价格：面议

---

产品详情

标准品编号:	D448593
名称:	Dihydrofluorescein diacetate
别名:	2-[3,6-Bis(acetyloxy)-9H-xanthen-9-yl]benzoic Acid
CAS号:	35340-49-9
分子式:	C₂₄H₁₈O₇
分子量:	418.4
种类:	Research Tools; Molecular Biology; Dyes;
应用:	Dihydrofluorescein diacetate is a chemical used for intracellular staining. Dihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Cell-loading studies indicate that dihydrofluorescein achieves higher intracellular concentrations than the other redox sensors such as 2',7'-dichlorodihydrofluorescein and Dihydrorhodamine 123. Dihydrofluorescein diacetate is first hydrolyzed by cellular esterases to dihydrofluorescein and is then oxidized to fluorescein primarily by hydrogen peroxide.
参考文献	1. Hempel, S L., et al., 1999. Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: comparison with 2',7'-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2',7'-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123. Free radical biology & medicine. 27(1-2): 146-59. PMID: 10443931