产品编号：D447075

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D447075
名称:	(1R)-1-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-2-[[(1S)-2-hydroxy-1-phenylethyl]amino]ethanol
别名:	(αR)-α-[[[(1S)-2-Hydroxy-1-phenylethyl]amino]methyl]-2,2-dimethyl-4H-1,3-benzodioxin-6-methanol
分子式:	C₂₀H₂₅NO₄
外观:	Solid
分子量:	343.42
溶解性:	Dichloromethane, Ethyl Acetate, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(αR)-α-[[[(1S)-2-Hydroxy-1-phenylethyl]amino]methyl]-2,2-dimethyl-4H-1,3-benzodioxin-6-methanol is an intermediate in the synthesis of Vilanterol Trifenatate-d4 (V260002). Vilanterol Trifenatate (V260000) is a long-acting β2 adrenergic receptor Agonist. It demonstrates prolonged bronchodilation in subjects with asthma and COPD.
参考文献	Procopiou, P., et al.: J. Med. Chem., 53, 4522 (2010); Kempsford, R., et al.: Pulm. Pharmacol. Ther., 26,