产品编号：D445615

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D445615
名称:	(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonyl Azide
CAS号:	378236-67-0
分子式:	C₁₀H₇F₂N₃O
分子量:	223.18
种类:	Building Blocks; Miscellaneous;
应用:	(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonyl Azide is a useful synthetic intermediate in the synthesis of Ticagrelor (T437700); the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is also used in the treatment of acute coronary syndromes (ACS).
参考文献	Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007); Zupancic, B., et al. PCT Int. Appl.ÂWOÂ2013144295ÂA1Â20131003. Oct 3, 2013