产品编号：D445605

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D445605
名称:	(αR)-N-[3-[3-(Difluoromethyl)phenyl]propyl]-α-methyl-1-naphthalenemethanamine
CAS号:	1025064-41-8
分子式:	C₂₂H₂₃F₂N
分子量:	339.42
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(αR)-N-[3-[3-(Difluoromethyl)phenyl]propyl]-α-methyl-1-naphthalenemethanamine is an impurity of Cinacalcet (C441800); an oral calcimimetic agent that modulates the calcium-sensing receptor, reduces parathyroid hormone (PHT) secretion, and lowers serum calcium and phosphorus concentrations in patients with endstage renal disease (ESRD) and secondary hyperparathyroidism (HPT).
参考文献	Block, G. A., et al.: N. Engl. J. Med., 350, 1516 (2004); Cunningham, J., et al.: Kidney Int., 68, 1793 (2005); Peacock, M., et al.: J. Clin. Endocr. Metab., 90 (2005); Lindberg, J. S., et al.: J. Am. Soc. Nephrol., 16, 800 (2005)