产品编号：D431735

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	D431735
名称:	1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester
CAS号:	942431-82-5
分子式:	C₂₀H₁₇Cl₂NO₄
分子量:	406.26
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 3-Chloroindomethacin (C367395), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO).
参考文献	Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)