产品编号：D422368

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D422368
名称:	Desmethyl Nintedanib Carboxylic Acid (Nintedanib Impurity A)
分子式:	C₂₉H₂₉N₅O₅
分子量:	527.57
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Desmethyl Nintedanib Carboxylic Acid is an impurity of Intedanib (I666650), which is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases. it is an indolinone as triple angiokinase inhibitors and an antitumor agent.
参考文献	Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)