产品编号：D293960

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D293960
名称:	Des-cyclohexenone Dihydrooxepinone Eplerenone
别名:	(2'R,5aS,5bR,6aR,7aS,10aS,10bR,11R)-Methyl 5a,7a-dimethyl-3,5'-dioxo-4,4',5,5a,5',6a,7,7a,9,10,10a,10b,11,12-tetradecahydro-3H,3'H-spiro[cyclopenta[5,6]oxireno[2',3':8,8a]naphtho[2,1-c]oxepine-8,2'-furan]-11-carboxylate
分子式:	C₂₄H₃₀O₇
分子量:	430.49
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
应用:	Des-cyclohexenone Dihydrooxepinone Eplerenone is an impurity of Eplerenone (E588775), a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
参考文献	de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),