产品编号：D293700

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D293700
名称:	Des(2-oxo-1-piperidinyl) 6-(4-(5-Amino-5-oxopentyl)) Apixaban
别名:	6-[4-[(5-Amino-5-oxopentyl)amino]phenyl]-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-Pyrazolo[3,4-c]pyridine-3-carboxamide
CAS号:	2187409-01-2
分子式:	C₂₅H₂₈N₆O₄
分子量:	476.53
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Des(2-oxo-1-piperidinyl) 6-(4-(5-Amino-5-oxopentyl)) Apixaban is a metabolite of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
参考文献	Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);