产品编号：D291870

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D291870
名称:	N-Desmethylhydroxyterbinafine
别名:	(5E)-2,2-Dimethyl-7-[(1-naphthalenylmethyl)amino]-5-hepten-3-yn-1-ol; (E)-2,2-Dimethyl-7-[(1-naphthalenylmethyl)amino]-5-Hepten-3-yn-1-ol
CAS号:	162227-14-7
分子式:	C₂₀H₂₃NO
分子量:	293.4
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Desmethylhydroxyterbinafine is the derivative of Hydroxy Terbinafine (H956160), which is a metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis.
参考文献	Gazinger, U., et al.: Proc. 13th Int. Congr. Chemother., 6, 116/52 (1983), Shadomy, S., et al.: Sabouraudia, 23, 125 (1985), Evans, E.G.V., et al.: Brit. Med. J., 318, 1031 (1999)