产品编号：D291115

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D291115
名称:	4-Deschloro-2-chloro-Sorafenib
别名:	4-​[4-​[[[[2-​Chloro-​3-​(trifluoromethyl)​phenyl]​amino]​carbonyl]​amino]​phenoxy]​-​N-​methyl-2-​pyridinecarboxamide
CAS号:	1431697-81-2
分子式:	C₂₁H₁₆ClF₃N₄O₃
外观:	白色至白色固体
熔点:	166-171°C
分子量:	464.82
储存:	冰箱保存
溶解性:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-Deschloro-2-chloro-Sorafenib is a derivative of Sorafenib (S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
参考文献	Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),