产品编号：D437800

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D437800
名称:	(4S)-4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Monomethyl Ester
别名:	(S)4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Monomethyl Ester
CAS号:	105580-47-0
分子式:	C₁₆H₁₅Cl₂NO₄
外观:	Beige Solid
分子量:	356.2
溶解性:	Dichloromethane, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(4S)-4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Monomethyl Ester is an intermediate in the synthesis of Felodipine, which is a dihydropyridine calcium channel blocker. Enantiomer S of Felodipine.
参考文献	Berntsson, P.B., et al.: Acta Pharm. Suec., 18, 221 (1981), Kratochwil, N., et al.: Biochem. Pharmacol., 64, 1355 (2002), O'Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Castilho, M., et al.: Bioorg. Med. Chem., 14, 516 (2006),