产品编号：D437245

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D437245
名称:	3,5-Dichloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
分子式:	C₁₁H₈Cl₂N₂O₃
分子量:	287.1
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3,5-Dichloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one is a metabolite of Apixaban (A726700), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
参考文献	Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);