产品编号：D289710

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	D289710
名称:	3-Descyano Febuxostat Ethyl Ester
别名:	4-Methyl-2-[4-(2-methylpropoxy)phenyl]-5-thiazolecarboxylic Acid Ethyl Ester; Ethyl 2-(4-Isobutoxyphenyl)-4-methylthiazole-5-carboxylate
CAS号:	144060-97-9
分子式:	C₁₇H₂₁NO₃S
外观:	白色至Beige Solid
分子量:	319.42
储存:	冰箱保存
溶解性:	Chloroform (Slightly), Methanol (Slightly, Heated)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-Descyano Febuxostat Ethyl Ester is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
参考文献	Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)