产品编号：D289335

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	D289335
名称:	Desacetyl Diltiazem Hydrochloride
别名:	(2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride; (2S-cis)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Monohydrochloride; Deacetyldiltiazem Hydrochloride
CAS号:	75472-91-2
参考CAS号:	42399-40-6 free base
分子式:	C₂₀H₂₅ClN₂O₃S
外观:	白色固体
熔点:	133-136°C
分子量:	408.94
储存:	-20°C Freezer, Under inert atmosphere
溶解性:	Chloroform (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
种类:	Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Desacetyl Diltiazem Hydrochloride is a metabolite of Diltiazem Hydrochloride (D460620), a calcium channel blocher with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV).
参考文献	Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987); Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990); Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991); Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971); Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998); Hansson, L., et al.: Lancet, 356, 359 (2000)

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