产品编号：D288430

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D288430
名称:	4-Deschloro-4-bromo-losartan Potassium Salt
别名:	Potassium 5-(4'-((4-bromo-2-butyl-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-yl)tetrazol-2-ide;
参考CAS号:	Free Base: 124749-81-1
分子式:	C₂₂H₂₂BrKN₆O
分子量:	505.45
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-Deschloro-4-bromo-losartan Potassium Salt is an impurity in the preparation of Losartan (L470500), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
参考文献	Chiu, T.A., et al.: J. Pharmacol. Exp. Ther., 252, 711 (1990), McIntyre, M., et al.: Pharmacol. Ther., 74, 181 (1997), Pitt, B., et al.: Lancet, 355, 1582 (2000); Gbenou, J. et al.: Mol. Biol. Rep., 40, 1127 (2013);