产品编号：D288247

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D288247
名称:	Desethyl Sacubitril-13C4
别名:	[S-(R*,S*)]-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid-13C4; (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic Acid-13C4; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid-13C4; Sacubitrilat-13C4; LBQ 657-13C4
参考CAS号:	类似: 149709-44-4
分子式:	C₁₈¹³C₄H₂₅NO₅
分子量:	387.41
种类:	Standards; Isotopic Labeled Analogues;
应用:	Desethyl Sacubitril=13C4 is the labelled, deuterated version of Desethyl Sacubitril which is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
参考文献	McMurray, J., et al.: N. Eng. J. Med., 371 (2014);