产品编号：D232935

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	D232935
名称:	2-Deoxy-D-erythro-pentopyranosyl Chloride Bis(4-methylbenzoate)(Decitabine Impurity)(Mixture of α/β isomers)
CAS号:	20535-28-8
参考CAS号:	α-Isomer: 20535-28-8/ β-Isomer: 516511-18-5
分子式:	C₂₁H₂₁ClO₅
分子量:	388.84
种类:	Research Tools;
应用:	2-Deoxy-D-erythro-pentopyranosyl chloride bis(4-methylbenzoate) is an impurity of Decitabine (α-isomer: D226730), a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, “normalizing” gene expression in cancerous cells.
参考文献	Aribi, A., et al.: Cancer, 109, 713 (2007); Issa, J., et al.: Blood, 103, 1635 (2004); Kantarjian , H., et al.: Cancer, 98, 522 (2003); Momparler, R., et al.: Anti-Cancer Drug., 8, 358 (1997); Plimack, E., et al.: Leukemia Lymphoma, 48, 1472 (2007)