产品编号：D231035

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D231035
名称:	N-Demethyl-3,4-dihydroxytamoxifen Hydrochloride(Z,E mixture)
别名:	4-[(Z,E)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-1,2-benzenediol Hydrochloride
CAS号:	2125720-11-6
参考CAS号:	Free Base: 2125720-10-5
分子式:	C₂₅H₂₈ClNO₃
外观:	Light Orange to Orange Solid
熔点:	163 - 165°C
分子量:	425.95
储存:	-20ËšC Freezer, Under Inert Atmosphere
溶解性:	Methanol (Slightly), Water (Slightly, Heated)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Demethyl-3,4-dihydroxytamoxifen is an metabolite of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor.
参考文献	Zhang, F., et al.: Chem. Rs. Toxicol., 13, 53 (2000); Sutherland, R., et al.: Nature, 267, 434 (1977); Lerner, L., et al.: Cancer Res., 50, 4177 (1990); Love, R., et al.: J. Clin. Oncol., 20 2559 (2002)