产品编号：D230787

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D230787
名称:	Demecolcine-d3
别名:	(7S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-benzo[a]heptalen-9(5H)-one-d3; Deacetylmethylcolchicine-d3; Colchamin-d3; NSC 3096-d3; Omain-d3; Omaine-d3; Reichstein's F-d3;N-Desacetyl-N-methylcolchicine-d3; Colcemid-d3;
CAS号:	1217668-72-8
参考CAS号:	类似: 477-30-5
分子式:	C₂₁H₂₂D₃NO₅
外观:	Faintly Yellow Crystalline Powder
熔点:	73-75°C
分子量:	374.45
溶解性:	Dichlormethane, DMSO, Methanol
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	An isotopically labelled antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
参考文献	Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),