产品编号：D230710

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D230710
名称:	Delanzomib
别名:	[(1R)-1-[[(2S,3R)-3-Hydroxy-1-oxo-2-[[(6-phenyl-2-pyridinyl)carbonyl]amino]butyl]amino]-3-methylbutyl]boronic Acid; CEP 18770; CIP 18770; CT 47098; NPH 007098; [(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic Acid;
CAS号:	847499-27-8
分子式:	C₂₁H₂₈BN₃O₅
外观:	白色固体
熔点:	178-190°C (dec.)
分子量:	413.28
储存:	Hygroscopic, -20ËšC Freezer, Under Inert Atmosphere
溶解性:	Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
种类:	Building Blocks; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Delanzomib is an orally active proteasome inhibitor. Delanzomib has been shown to down-modulate NF-κB, induce apoptosis, inhibit angiogenesis and M-CSF-RANKL-induced osteoclastogenesis.
参考文献	Piva, R. et al.: Blood, 111, 2765 (2008); Sanchez, E. et al.: Br. J. Haematol., 148, 569 (2010);