产品编号：D230653

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D230653
名称:	Dehydroxy-(2-methyl-4-(2-methylbenzamido)benzoate) Tolvaptan
别名:	4-[(2-Methylbenzoyl)amino]-2-methylbenzoic Acid 1-[4-[(2-Methylbenzoyl)amino]-2-methylbenzoyl]-7-chloro-2,3-dihydro-1H-benzo[b]azepin-5-yl Ester;
CAS号:	1580889-36-6
分子式:	C₄₂H₃₆ClN₃O₅
分子量:	698.21
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Dehydroxy-(2-methyl-4-(2-methylbenzamido)benzoate) Tolvaptan is the impurity of the drug Tolvaptan (T536650), which is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
参考文献	Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006);