产品编号：D101002

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D101002
名称:	Dabrafenib-d9
别名:	N-[3-[5-(2-Amino-4-pyrimidinyl)-2-[1,1-di(methyl-d3)ethyl-2,2,2-d3]-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamide; GSK 2118436-d9; Tafinlar-d9
CAS号:	1423119-98-5
参考CAS号:	未标记：1195765-45-7
分子式:	C₂₃H₁₁D₉F₃N₅O₂S₂
分子量:	528.62
种类:	Research Tools;
应用:	Dabrafenib-d9 is the isotope labelled analog of Dabrafenib (D101000); an inhibitor of mutated BRAF kinase. Dabrafenib also has clinical activity with a manageable safety profile in clinical trials of phase 1 and 2 in patients with BRAF(V600)-mutated metastatic melanoma.
参考文献	Hauschild, A., et al.: Lancet, 380, 358 (2012); Falchook, G.S., et al.: Lancet, 379, 1893 (2012); Ascierto, P.A., et al.: J. Clin. Oncol., 31, 3205 (2013)