产品编号：C988367
产品规格：1mg
产品价格：面议
| 标准品编号: | C988367 |
| 名称: | 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4] diazepin-6-one-d2 |
| 别名: | 11-Cyclopropyl-4-(hydroxymethyl)-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6(11H)-one-d2 |
| 参考CAS: | 未标记: 133627-24-4 |
| 分子式: | C₁₅H₁₂D₂N₄O₂ |
| 外观: | Yellow Solid |
| 分子量: | 284.31 |
| 储存: | -20°C Freezer |
| 溶解度: | Chloroform, Methanol |
| 类别: | Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Benzodiazepines; |
| 应用: | 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4] diazepin-6-one-d2 is a labelled analogue of 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4] diazepin-6-one (C988365), which is a metabolite of Nevirapine (N391275), which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. It is also an antiviral. 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4] diazepin-6-one-d2 is also an intermediate in synthesizing Nevirapine-d2 (N391276), an isotope labelled Nevirapine (N391275), which acts as a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral. |
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