产品编号:C858805
产品规格:2.5mg
产品价格:面议
| 标准品编号: | C858805 |
| 名称: | CX08005 |
| 别名: | 2-[[[2-(Tetradecyloxy)phenyl]amino]carbonyl]benzoic Acid |
| CAS号: | 1256341-22-6 |
| 分子式: | C₂₈H₃₉NO₄ |
| 分子量: | 453.61 |
| 类别: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | CX08005 is a competitive PTP1B inhibitor (IC50 = 0.781 μM). Binds catalytic P-loop of enzyme. Improves insulin sensitivity in obese mice in the glucose tolerance test and the homeostasis model assessment of insulin resistance index (HOMVIP(LA)IR). Enhances insulin-induced glucose uptake in adipocytes and myotubes in vitro. Exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP. |
| 参考文献 | |