CX08005

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产品编号:C858805

产品规格:2.5mg

产品价格:面议


产品详情

标准品编号: C858805
名称: CX08005
别名: 2-[[[2-(Tetradecyloxy)phenyl]amino]carbonyl]benzoic Acid
CAS号: 1256341-22-6
分子式: C₂₈H₃₉NO₄
分子量: 453.61
类别: Standards; Enzyme Activators and Inhibitors;
应用: CX08005 is a competitive PTP1B inhibitor (IC50 = 0.781 μM). Binds catalytic P-loop of enzyme. Improves insulin sensitivity in obese mice in the glucose tolerance test and the homeostasis model assessment of insulin resistance index (HOMVIP(LA)IR). Enhances insulin-induced glucose uptake in adipocytes and myotubes in vitro. Exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP.
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