产品编号：C781600

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	C781600
名称:	CP 43
别名:	N-[2-Oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide
CAS号:	850467-66-2
分子式:	C₂₅H₂₄N₂O₂
分子量:	384.47
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	CP 43 is a potent TAO kinase (TAOK) inhibitor (IC50 values are 11 nM/L and 15 nM/L for TAOK1 and TAOK2, respectively). Inhibits TAOK phosphorylation and activation of JNK in vitro. Also prolongs duration of mitosis and increases mitotic cell death in the SKBR3 breast cancer cell line.
参考文献	Koo, Chuay-Yeng, et al. Mol Cancer Ther., (2017). Xu, Wei., et al.; PCT Int. Appl., ÂWOÂ2005040355ÂA2Â20050506 Â(2005)