产品编号：C432695

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	C432695
名称:	CI-988
别名:	4-[[(1R)-2-[[(2R)-3-(1H-Indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic Acid; CI 988; [R-(R*,R*)]-4-[[2-[[3-(1H-Indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic Acid;
CAS号:	130332-27-3
分子式:	C₃₅H₄₂N₄O₆
分子量:	614.73
类别:	Research Tools;
应用:	CI-988 is a potent and selective cholecystokinin 2 (CCK-2) receptor antagonist that displays ~ 1600-fold selectivity over CCK1 receptors and has negligible affinity at other binding sites. CI-988 exhibits anxiolytic activity following oral administration. CI-98 inhibited the proliferation of small cell lung cancer (SCLC) cells in mice.
参考文献	Drysdale, M. et al.: Bioorg. Med. Chem. Lett., 2, 45 (1992); Moody, T.W. et al.: J. Pharmacol. Exp. Ther., 299, 1154 (2001);