产品编号：C374050
产品规格：5mg
产品价格：面议
| 标准品编号: | C374050 |
| 名称: | 2-Chloro-5-nitro-N-4-phenylbenzamide |
| 别名: | GW9662 |
| CAS号: | 22978-25-2 |
| 分子式: | C₁₃H₉ClN₂O₃ |
| 外观: | 白色至白色固体 |
| 熔点: | 157-159°C |
| 分子量: | 276.68 |
| 储存: | 冰箱保存 |
| 溶解度: | DMSO (Slightly),Methanol (Slightly) |
| 类别: | Building Blocks; Miscellaneous; |
| 应用: | A cell-permeable, selective and irreversible PPARγ antagonist (IC50 = 3.3 nM, 32 nM, and 2 µM for PPARγ, PPARα, and PPARδ, respectively). Reported to covalently modify a cysteine residue in the binding site of PPAR. At a concentration of 10 µM, also acts as an agonist of human pregnane X receptor (PXR) and farnesoid X receptor (FXR). Does not activate liver X receptor-a (LXRa), retinoic acid receptor (RAR), retinoid X receptor-a (RXRa) and thyroid receptors a and b (TRa and TRb |
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