产品编号：C367730

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	C367730
名称:	5-Chloro-1-(2-fluorophenyl)pentan-2-one
别名:	5-Chloro-1-(2-fluorophenyl)-2-pentanone
CAS号:	1056459-35-8
分子式:	C₁₁H₁₂ClFO
分子量:	214.66
类别:	Building Blocks; Miscellaneous;
应用:	5-Chloro-1-(2-fluorophenyl)pentan-2-one is an intermediate in the synthesis of Prasugrel (P701150). Prasugrel is a novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome.
参考文献	Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),