产品编号：C349270

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	C349270
名称:	2-​Chloro-​1-​(3-​fluorobenzyloxy)​-​4-​nitrobenzene
别名:	2-Chloro-1-[(3-fluorophenyl)methoxy]-4-nitrobenzene; 1-Fluoro-3-[(4-nitro-2-chlorophenoxy)methyl]benzene;2-Chloro-1-(3-fluorobenzyloxy)-4-nitrobenzene; 3-Chloro-4-[(3-fluorobenzyl)oxy]nitrobenzene; 4-(3-Fluorobenzyloxy)-3-chloronitrobenzene;
CAS号:	443882-99-3
分子式:	C₁₃H₉ClFNO₃
分子量:	281.67
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-​Chloro-​1-​(3-​fluorobenzyloxy)​-​4-​nitrobenzene is a reagent used in the synthesis of novel indole-2-carboxamide derivative as anti-inflammatory agents used in the treatment of sepsis. Also an intermediate of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCVIP(LA)1 and -2 mutant tumors.
参考文献	Liu, Z. et al.: J. Med. Chem., 59, 4637 (2016); Jones, P., et al.: J. Med. Chem., 52, 7170 (2009); Giannini, G., et al.: Bioorg. Med. Chem. Lett., 24, 462 (2014);