产品编号：C179120

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	C179120
名称:	3-((5-Chloro-4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
分子式:	C₂₈H₂₁ClF₃N₇O
外观:	Pale Yellow to Pale Green Solid
熔点:	>245°C (dec.)
分子量:	563.96
储存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-((5-Chloro-4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide, is an impurity of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia.
参考文献	Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),